Intron 5α of the COXI gene of yeast mitochondrial DNA is a mobile group I intron
نویسندگان
چکیده
منابع مشابه
Intron open reading frames as mobile elements and evolution of a group I intron.
Group I introns are proposed to have become mobile following the acquisition of open reading frames (ORFs) that encode highly specific DNA endonucleases. This proposal implies that intron ORFs could behave as autonomously mobile entities. This was supported by abundant circumstantial evidence but no experiment of ORF transfer from an ORF-containing intron to its ORF-less counterpart has been de...
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Eukaryotic evolution has been characterized by intron loss. In eukaryotes, the proposed mechanisms of intron loss are exonization, random genomic deletion, retroprocessing and most recently, horizontal gene transfer followed by gene conversion (HGT-GC). Here we investigate the mechanism of intron loss from the mitochondrial cox2 gene, which in previous studies has shown a variable intron distri...
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Riboswitches are mRNA-based elements that regulate gene expression via binding of a specific ligand. Breaker and coworkers have now discovered a novel type of regulatory RNA motif that acts by c-di-GMP-dependent control of a self-splicing group I intron ribozyme (Lee et al., 2010).
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Mobile group I introns are hypothesized to have arisen after invasion by endonuclease-encoding open reading frames (ORFs), which mediate their mobility. Consistent with an endonuclease-ORF invasion event, we report similarity between exon junction sequences (the recognition site for the mobility endonuclease) and intron sequences flanking the endonuclease ORF in the sunY gene of phage T4. Furth...
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provide extensive genome sequencing within dogs and cats to map their genetic diversity. The rewards of these efforts for evolutionary biology are considerable. Well-resolved phylogenetic trees of most carnivore families were early accomplishments. Efforts to map genome diversity have found signals of selection in regions that can be related to specific phenotypes. In the dog, the genetic basis...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1992
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/20.15.4069